Douxo S3 Pyo Shampoo for Dogs & Cats – 3% Chlorhexidine Antiseptic & Hydrating Relief

Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL)

Douxo S3 Pyo Shampoo: 3% Chlorhexidine & 0.5% Ophytrium – Antiseptic & Hydrating Relief for Dogs & Cats (6.7 oz)

Douxo S3 Pyo Shampoo is a veterinarian-recommended antiseptic and hydrating formula that combines 3% Chlorhexidine with 0.5% Ophytrium. Specifically designed for dogs and cats suffering from bacterial or yeast skin infections, this 6.7 fl. oz. (200mL) shampoo gently cleanses, soothes irritation, and helps restore the skin barrier. With over 7,000 ratings and 10,000+ bought in the past month, it's a trusted solution for pet parents. Save 12% at just $21.99 (list $24.99).
Douxo S3 Pyo cleans deep to manage bacterial infections
Deep cleansing action targets bacteria & yeast at the source
Ophytrium hydrates and soothes sensitive skin
Ophytrium technology hydrates while reducing inflammation
Gentle enough for cats and dogs with recurring skin issues
Safe for both dogs & cats — ideal for multi-pet households
Veterinarian preferred formula for dermatological support
Veterinarian preferred — backed by clinical research
Rating
4.7 / 5.0
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Price
$21.99 (Save 12%)
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Active Ingredients
3% Chlorhexidine + 0.5% Ophytrium
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Size
6.7 fl. oz. (200mL)
🛒 Check Lowest Price on Amazon

⭐ What Pet Parents Are Saying

Jessica M. (Golden Retriever Owner) ★★★★★ Verified Purchase
“After months of dealing with my dog's yeasty paws and constant licking, this shampoo was a lifesaver. Within two baths, the redness reduced significantly. The Ophytrium really seems to help with moisture balance. Highly recommend!”
Dr. Patel (Veterinarian Review) ★★★★★ Verified Purchase
“I recommend Douxo S3 Pyo to my clients for pyoderma and Malassezia. The 3% chlorhexidine is potent against bacteria, and unlike older formulas, the Ophytrium prevents dryness and irritation. Excellent choice for maintenance therapy.”
Carlos R. (Cat with Ringworm History) ★★★★★ Verified Purchase
“My rescue cat came with persistent fungal spots. This shampoo is gentle enough for feline skin but effective. It lathers well and the scent is mild. Her coat is soft and the lesions have finally cleared.”

❓ Frequently Asked Questions

How often should I bathe my pet with Douxo S3 Pyo?
For active infections, veterinarians typically recommend 2-3 times per week for 2-3 weeks, then as needed for maintenance. Always follow your vet's advice based on your pet's condition.
Is this safe for cats? Does it require a prescription?
Yes, it is safe for both dogs and cats over 6 weeks of age. No prescription is needed — it's an over-the-counter veterinary-strength shampoo, but consult your vet before use for chronic conditions.
Will this dry out my pet's skin like other medicated shampoos?
No. The 0.5% Ophytrium is a unique patented ingredient that supports the skin barrier and provides hydration, counteracting the drying effects of chlorhexidine. Many users report softer coats after use.
How long until I see improvement?
Most owners notice reduced odor and itching after the first 1-2 baths. Visible reduction in redness, scaling, or pustules often occurs within 5-7 days of consistent use.
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